Column purification

Column purification is a method in which a cylindrical container, or column, is filled with a packing material possessing various physicochemical properties, and the substance to be purified is dissolved in a solvent and poured into the column. Separation and purification are achieved by utilizing the difference in affinity between the packing material and the solvent passed through it, as well as the difference in molecular size.

Fukui Canon Materials' Column Purification Technology

We have a range of columns supporting different scales of production. This enables seamless process development from laboratory scale through to mass production, with early-stage consideration of optimal large-scale production conditions. Leveraging our years of expertise in purification, concentration, and synthesis, we recover high-purity materials from raw materials containing multiple impurities by using optimally formulated conditions.

Column Purification Diagram (Representative Example)

Column Purification Diagram (Representative Example)

Column Purification Track Record

For many years, we have been purifying and supplying a wide range of substances as a chemical materials hub for the Canon Group.

  • Purification is available for a variety of applications, including:
  • Impurity removal from heat-sensitive substances for enhanced purity
  • Decolorization and deodorization of materials

Large-scale purification
Feel free to contact us regarding large-scale purification or other specific requirements.

Examples of Processing Capacity

Several kg/lot 10 kg/month
10kg/ LOT 100 kg/month
100kg/ LOT 1,000 kg/month

Examples of Materials Processed

Electrophotographic photoreceptor materials
Aromatic compound monomers
Acrylic monomers *Expertise in polymerization inhibition
Epoxy monomers

and others

Column Purification Equipment

We have column equipment of various capacities, enabling us to handle volumes ranging from small quantities up to several tens of tons per year, depending on requirements. We can also purify a diverse range of substances, both solid and liquid.

Column Equipment Overview

Material SUS (compatible with various solvents)
Column temperature control Up to 80°C
Container temperature Up to 120°C (suitable for low-solubility materials)
Number of units 12
Column diameter φ150mm〜φ950mm (various sizes)
Column Equipment

Case Example Using Column Purification

We optimize the adsorbent and elution solvent to efficiently remove impurities that affect product properties. We can perform not only purity analysis using HPLC and GC, but also quality control with our in-house facilities.

Column graph
Example: Synthesis, column separation, and purification using low-cost raw materials
*HPLC measurement data

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